(Bromomethyl)cyclopentane → HCID 67049856, compound

HRID 1875800Notes

Reaction equation

HRID 1875800 reaction equation
[CH3:1][O:2][C:3](=[O:30])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][N:11]2[C:15]3[CH:16]=[C:17]([F:21])[C:18]([F:20])=[CH:19][C:14]=3[N:13]=[C:12]2[C:22]2[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][C:23]=2[OH:29])[CH:5]=1.Br[CH2:32][CH:33]1[CH2:37][CH2:36][CH2:35][CH2:34]1>>[CH3:1][O:2][C:3](=[O:30])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][N:11]2[C:15]3[CH:16]=[C:17]([F:21])[C:18]([F:20])=[CH:19][C:14]=3[N:13]=[C:12]2[C:22]2[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][C:23]=2[O:29][CH2:32][CH:33]2[CH2:37][CH2:36][CH2:35][CH2:34]2)[CH:5]=1

Participants

3

Reactant 2

HCID 12723264(Bromomethyl)cyclopentaneHCID 136378486HCID 136378486, compound

Product 1

HCID 67049856HCID 67049856, compound

Procedure

The title compound was prepared in analogy to Example 5, intermediate a, from 3-[2-(4-chloro-2-hydroxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-benzoic acid methyl ester and bromomethyl-cyclopentane (CAS Reg. No. 3814-30-0). Brown sticky solid (72%). MS (Turbo Spray): m/z=511.2 (M+H).

Sources & evidence

ORD record
ord-0fa10cb160bc400e949a438574021535
Source dataset
uspto-grants-2012_11
Patent number
US08309581B2

Reaction notes

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