HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexane, (bromomethyl)- → 2-(2-bromo-phenyl)-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexane, (bromomethyl)- | HCID 137636 | — |
| Reactant | 3-{4-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-phenyl}-propionic acid | HCID 58209258 | — |
| Reactant | 2-(2-bromo-phenyl)-5,6-difluoro-1H-benzoimidazole | HCID 60981492 | — |
| Product | 2-(2-bromo-phenyl)-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole | HCID 67049989 | — |
Reaction Steps
The title compound was prepared in analogy to Example 19, intermediate b, from 2-(2-bromo-phenyl)-5,6-difluoro-1H-benzoimidazole and bromomethyl-cyclohexane (2550-36-9). Yellow sticky solid (94%). MS (Turbo Spray): m/z=406.1 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309581B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-bc9e8529796e4c9ea96e131f689cb18c |
| Source note | uspto-grants-2012_11 |