Methanol → HCID 178497604, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2-fluoro-4-(1H-tetrazol-5-yl)-benzoic acid (100 mg, 0.48 mmol) in methanol (5 ml), thionyl chloride (0.5 ml) was added at 0° C. and the reaction mixture was stirred at 25° C. for 12 h. The solvents were distilled off in vacuo, and the residue was purified by chromatography over silica gel (5% methanol/dichloromethane) to afford the title compound as a yellow solid (58%). MS (Turbo Spray): m/z=222.0 (M+H).

Provenance & Evidence