HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)-3-fluorobenzonitrile → HCID 67050044, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)-3-fluorobenzonitrile | HCID 2783149 | — |
| Reactant | 3-{4-[2-(4-Chloro-2-cyclopentylmethoxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-phenyl}-propionic acid | HCID 58209258 | — |
| Reactant | HCID 178505395 | HCID 178505395 | — |
| Product | HCID 67050044 | HCID 67050044 | — |
Reaction Steps
The title compound was prepared in analogy to Example 19, intermediate b, from 5,6-difluoro-2-(2-methoxy-phenyl)-1H-benzoimidazole (Example 34, intermediate d) and 4-bromomethyl-3-fluoro-benzonitrile (CAS Reg. No. 105942-09-4). Blue solid (32%). MS (Turbo Spray): m/z=394.4 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309581B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-2dda12effceb4e51915d120d0199ebc1 |
| Source note | uspto-grants-2012_11 |