2,3-Dimethoxyaniline → 2-Chloro-N-(2,3-dimethoxyphenyl)quinazolin-4-amine

Participants

Reaction Steps

The title compound was prepared from 2,4-dichloroquinazoline and 2,3-dimethoxyaniline by a procedure similar to Example 28 (84% yield). 1H NMR (CDCl3): 8.57 (s, broad, 1H), 8.38 (d, J=8.4 Hz, 1H), 7.77-7.86 (m, 3H), 7.55-7.61 (m, 1H), 7.15 (t, J=8.7 Hz, 1H), 6.73-6.75 (m, 1H), 4.00 (s, 3H), 3.91 (s, 3H).

Provenance & Evidence