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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1876093Generated: November 2, 2026

Ethanolamine → HCID 57938786, compound

https://huagongshe.com/reaction/1876093

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolamineHCID 700—
Reactant(2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methylamineHCID 11558497—
ProductHCID 57938786HCID 57938786—

Reaction Steps

The title compound was prepared from (2-chloro-quinazolin-4-yl)-(6-methoxy-pyridin-3-yl)-methyl-amine (12 mg, 0.040 mmol) and ethanolamine (28 μl) by a procedure similar to Example 10 and was isolated as off white solid (8 mg, 66%). 1H NMR (CDCl3): 8.03 (brd, J=3.0 Hz, 1H), 7.47-7.35 (m, 3H), 6.91 (brd, J=8.7 Hz, 1H), 6.78-6.73 (m, 2H), 5.56 (brs, 1H), 3.94 (s, 3H), 3.93-3.90 (m, 2H), 3.70-3.56 (m, 2H), 3.48 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309562B2
Source datasetuspto-grants-2012_11
ORD IDord-de3a03ff3691463a889f0acd34016f4f
Source noteuspto-grants-2012_11