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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1876114Generated: November 1, 2026

Methyl iodide → N-(4-Methoxyphenyl)-N-methyl-2-phenylquinazolin-4-amine

https://huagongshe.com/reaction/1876114

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantN-(4-methoxyphenyl)-2-phenylquinazolin-4-amineHCID 719284—
ProductN-(4-Methoxyphenyl)-N-methyl-2-phenylquinazolin-4-amineHCID 57938808—

Reaction Steps

The title compound was prepared from (4-methoxy-phenyl)-(2-phenyl-quinazolin-4-yl)-amine (51 mg, 0.16 mmol) and methyl iodide (0.07 ml, 1.09 mmol) by a procedure similar to Example 36. 1H NMR (CDCl3): 8.64-8.61 (m, 2H), 7.90 (d, J=8.4 Hz, 1H), 7.59-7.48 (m, 4H), 7.18-7.14 (m, 2H), 7.08-6.98 (m, 2H), 6.94-6.91 (m, 2H), 3.85 (s, 3H), 3.73 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309562B2
Source datasetuspto-grants-2012_11
ORD IDord-15688abb52ac4a62bf8ba256e5f23d30
Source noteuspto-grants-2012_11