HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-methylquinazoline → N-(2-Fluoro-4-methoxyphenyl)-2-methylquinazolin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-methylquinazoline | HCID 2785421 | — |
| Reactant | 2-Fluoro-4-methoxyaniline | HCID 3756383 | — |
| Product | N-(2-Fluoro-4-methoxyphenyl)-2-methylquinazolin-4-amine | HCID 42625911 | — |
Reaction Steps
The title compound was prepared from 4-chloro-2-methylquinazoline and 2-fluoro-4-methoxyaniline by a procedure similar to Example 28 (79%). 1H NMR (CDCl3): 8.54 (m, 1H), 7.83 (m, 2H), 7.65 (m, 1H), 7.50 (m, 1H), 7.47 (s, broad, 1H), 6.74-6.81 (m, 2H), 3.83 (s, 3H), 2.70 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309562B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-d421c3e008714a049de25c3b2438bd6d |
| Source note | uspto-grants-2012_11 |