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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1876129Generated: October 27, 2026

4-(Methylamino)benzoic acid → Benzoic acid, 4-[methyl(2-methyl-4-quinazolinyl)amino]-

https://huagongshe.com/reaction/1876129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Methylamino)benzoic acidHCID 66345—
Reactant4-Chloro-2-methylquinazolineHCID 2785421—
ProductBenzoic acid, 4-[methyl(2-methyl-4-quinazolinyl)amino]-HCID 11185473—

Reaction Steps

The title compound was prepared from 4-chloro-2-methylquinazoline and 4-(methylamino)benzoic acid by a procedure described for Example 1b. 1H NMR (CDCl3): 8.42-8.39 (m, 1H), 8.28 (m, 2H), 7.84 (m, 1H), 7.45 (m, 2H), 7.37 (m, 1H), 7.22 (m, 1H), 6.84 (d, J=1H, 8.4), 3.91 (s, 3H), 3.01 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08309562B2
Source datasetuspto-grants-2012_11
ORD IDord-921e4dd967f842e79fbff69ec058840e
Source noteuspto-grants-2012_11