6-Bromo-4-chloro-2-methylquinazoline → HCID 59242064, compound

Participants

Reaction Steps

A mixture of 0.21 g (0.82 mmol) of 6-bromo-4-chloro-2-methyl-quinazoline and 0.16 g (0.89 mmol) of (4-ethoxy-3-fluoro-phenyl)-methyl-amine in i-PrOH (20 mL) was stirred at ambient temperature for 18 hours. The precipitate was collected and washed with Et2O to give 0.1 g of the title compound as the HCl salt. 1H NMR (DMSO-d6) δ 8.32-6.8 (6H), 4.23 (q, 2H), 3.72 (s, 3H), 2.73 (s, 3H), 1.39 (t, 3H); LC-MS (ESI+; 391 ([M+H]+)).

Provenance & Evidence