Isatin → HCID 178523949, compound

Participants

Reaction Steps

The title compound was prepared as a yellow solid, using isatin 7 and benzhydrazide according to the synthetic method D. The resulting solid was washed with ethanol. Yield: 71.4%. 1H NMR (DMSO-d6): δ 1.05-1.09 (m, 2H), 1.18-1.20 (m, 3H), 1.61-1.79 (m, 6H), 3.65 (d, J=7.5 Hz, 2H), 7.22 (t, J=8 Hz, 1H), 7.28 (d, J=8 Hz, 1H), 7.52 (t, J=7.5 Hz, 1H), 7.66-7.70 (m, 3H), 7.75 (t, J=7 Hz, 1H), 7.96 (d, J=7 Hz, 2H), 13.97 (br s, 1H). 13C NMR (DMSO-d6): δ 25.68 (CH2), 26.26 (CH2), 30.71 (CH2), 36.40 (CH), 45.90 (CH2), 110.95 (CH), 119.57 (C), 121.19 (CH), 123.67 (CH), 127.87 (CH), 129.68 (CH), 132.19 (CH), 132.44 (C), 133.40 (CH), 137.70 (C), 143.94 (C═N), 161.90 (C═O), 163.42 (C═O). HRMS (ES+) calcd for C22H24N3O2 (M+H+), m/e, 362.1872; found, 362.1863.

Provenance & Evidence