2,2-Dimethylpropanehydrazide → HCID 178446196, compound

HRID 1876275Notes

Reaction equation

HRID 1876275 reaction equation
[CH2:1]([N:6]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([O:17][CH3:18])[CH:15]=2)[C:9](=O)[C:7]1=[O:8])[CH2:2][CH2:3][CH2:4][CH3:5].[CH3:19][C:20]([CH3:26])([CH3:25])[C:21]([NH:23][NH2:24])=[O:22]>>[CH3:18][O:17][C:14]1[CH:15]=[C:16]2[C:11](/[C:9](=[N:24]/[NH:23][C:21](=[O:22])[C:20]([CH3:26])([CH3:25])[CH3:19])/[C:7](=[O:8])[N:6]2[CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 5451472,2-DimethylpropanehydrazideHCID 251944561-Pentyl-6-methoxy-isatin

Product 1

HCID 178446196HCID 178446196, compound

Procedure

The title compound was prepared as a yellow solid, using 1-pentyl-6-methoxy-isatin obtained in Example 39(A) and 2,2-Dimethylpropionic acid hydrazide according to the synthetic method E. NMR (CDCl3): δ 0.91 (t, 3H), 1.36 to 1.39 (m, 13H), 1.69-1.75 (m, 2H), 3.70 (t, 2H), 3.87 (s, 3H), 6.42 (d, 1H), 6.62 (dd, 1H), 7.74 (d, 2H), 13.34 (br s, 1H).

Sources & evidence

ORD record
ord-ded2b5b71f624e7798258856c3e840c5
Source dataset
uspto-grants-2012_11
Patent number
US08309595B2

Reaction notes

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