HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68701031, compound → HCID 86646306, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68701031 | HCID 68701031 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86646306 | HCID 86646306 | — |
Reaction Steps
A solution of 250 mg of (S)-1-[(7-Triethylsilanylethynyl-naphthalen-1-ylmethyl)-carbamoyl]-pyrrolidine-2-carboxylic acid in 14 ml of THF is stirred at rt for 1 hour. Solvent is evaporated and the residue obtained is purified by preparative HPLC (Waters Sun Fire C18 column, gradient water/acetonitrile 95/5 to 0/100) to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309596B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-17d38dfbbaff4c8bb0074989e0308e14 |
| Source note | uspto-grants-2012_11 |