HCID 13450497, compound → HCID 61349231, compound

HRID 1876863Notes

Reaction equation

HRID 1876863 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][CH2:13][O:12][C:11]2=[O:16])=[CH:6][CH:5]=1)([O-])=O.[H][H]>CO.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([N:10]2[CH2:15][CH2:14][CH2:13][O:12][C:11]2=[O:16])=[CH:8][CH:9]=1

Participants

5

Reactant 2

HCID 13450497HCID 13450497, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 61349231HCID 61349231, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 3-(4-nitrophenyl)-1,3-oxazinan-2-one (0.10 g, 0.00045 mol) in 5 mL of methanol was hydrogenated, in the presence of 10% Pd/C, under balloon pressure of hydrogen, overnight. After filtering off the catalyst, the filtrate was evaporated to dryness and used directly in next step. LCMS (M+H) 193.0.

Workup

  1. filtrationAfter filtering off the catalyst
  2. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-dd0f5425be694dc5ac0bfb41a9e9e57e
Source dataset
uspto-grants-2012_11
Patent number
US08309718B2

Reaction notes

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