反应详情

The cis- and trans-isomers of the titled compound were prepared as a racemic mixture according to the procedure described in example 306, using 3-(4-(2-chloropyrimidin-4-yl)-1H-pyrazol-1-yl)-3-(cyanomethyl)-cyclobutanecarbonitrile and 1-[2-(4-nitrophenoxy)ethyl]pyrrolidine as starting materials. First isomer retention time 1.055 min, LCMS (M+H) 469.4. Second peak retention time 1.072 min, LCMS (M+H) 469.4.