Ethyl 3-(methylamino)propanoate → HCID 59529315, compound

HRID 1876937Notes

Reaction equation

HRID 1876937 reaction equation
[CH2:1]([C:3]1[O:4][C:5]([C:19]2[CH:24]=[CH:23][C:22]([C:25]([F:28])([F:27])[F:26])=[CH:21][CH:20]=2)=[CH:6][C:7]=1[CH2:8][O:9][C:10]1[CH:18]=[CH:17][C:13]([C:14](O)=[O:15])=[CH:12][CH:11]=1)[CH3:2].[CH3:29][NH:30][CH2:31][CH2:32][C:33]([O:35]CC)=[O:34]>>[CH2:1]([C:3]1[O:4][C:5]([C:19]2[CH:20]=[CH:21][C:22]([C:25]([F:28])([F:26])[F:27])=[CH:23][CH:24]=2)=[CH:6][C:7]=1[CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]([C:14]([N:30]([CH3:29])[CH2:31][CH2:32][C:33]([OH:35])=[O:34])=[O:15])=[CH:17][CH:18]=1)[CH3:2]

Participants

3

Reactant 2

HCID 541480Ethyl 3-(methylamino)propanoateHCID 68514453HCID 68514453, compound

Product 1

HCID 59529315HCID 59529315, compoundYield 90%

Procedure

An operation similar to that in Example 1 (4) was performed using 4-({2-ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methoxy)benzoic acid (117 mg) as well as ethyl 3-(methylamino)propanoate (47 mg) to give the title compound (128 mg, 90%) as an oil.

Sources & evidence

ORD record
ord-f3fb30c8e86943f6b69e65589974a177
Source dataset
uspto-grants-2012_11
Patent number
US08309580B2

Reaction notes

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