HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde → 1-{2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}-3-methylbutan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde | HCID 23074355 | — |
| Reactant | HCID 178420648 | HCID 178420648 | — |
| Product | 1-{2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}-3-methylbutan-1-ol | HCID 68513344 | 83% |
Reaction Steps
An operation similar to that in Example 3 (2) was performed using 2-ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde (805 mg) and 1N isobutylmagnesium bromide-tetrahydrofuran solution (6.0 mL) to give the title compound (819 mg, 83%) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309580B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-f48eec13cb6e43389fa47c6a5b98254b |
| Source note | uspto-grants-2012_11 |