HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde → Cyclohexyl{2-ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde | HCID 23074355 | — |
| Reactant | HCID 178420632 | HCID 178420632 | — |
| Product | Cyclohexyl{2-ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol | HCID 68515529 | 76% |
Reaction Steps
An operation similar to that in Example 3 (2) was performed using 2-ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde (1.21 g) and 1N cyclohexylmagnesium bromide-tetrahydrofuran solution (6.8 mL) to give the title compound (1.21 g, 76%) as a yellow crystal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309580B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-da38a75907ab46af861bc825ac5cd397 |
| Source note | uspto-grants-2012_11 |