HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde → {2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}(phenyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde | HCID 23074355 | — |
| Reactant | HCID 178420626 | HCID 178420626 | — |
| Product | {2-Ethyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}(phenyl)methanol | HCID 68511675 | 87% |
Reaction Steps
An operation similar to that in Example 3 (2) was performed using 2-ethyl-5-[4-(trifluoromethyl)phenyl]-3-furaldehyde (1.0 g) and 1N phenylmagnesium bromide-tetrahydrofuran solution (8.0 mL) to give the title compound (1.2 g, 87%) as a yellow crystal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309580B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-7f9bfd3590654431beeac520ab741d46 |
| Source note | uspto-grants-2012_11 |