Ethyl 3-(methylamino)propanoate → HCID 59529331, compound

HRID 1876965Notes

Reaction equation

HRID 1876965 reaction equation
[CH:1]1([CH:7]([C:18]2[CH:22]=[C:21]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=3)[O:20][C:19]=2[CH3:30])[O:8][C:9]2[CH:17]=[CH:16][C:12]([C:13](O)=[O:14])=[CH:11][CH:10]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:31][NH:32][CH2:33][CH2:34][C:35]([O:37]CC)=[O:36]>>[CH:1]1([CH:7]([C:18]2[CH:22]=[C:21]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=3)[O:20][C:19]=2[CH3:30])[O:8][C:9]2[CH:17]=[CH:16][C:12]([C:13]([N:32]([CH3:31])[CH2:33][CH2:34][C:35]([OH:37])=[O:36])=[O:14])=[CH:11][CH:10]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 541480Ethyl 3-(methylamino)propanoateHCID 68513337HCID 68513337, compound

Product 1

HCID 59529331HCID 59529331, compoundYield 82%

Procedure

An operation similar to that in Example 1 (4) was performed using 4-{cyclohexyl[5-(4-fluorophenyl)-2-methyl-3-furyl]methoxy}benzoic acid (163 mg) as well as ethyl 3-(methylamino)propanoate (63 mg) to give the title compound (161 mg, 82%) as an amorphous compound.

Sources & evidence

ORD record
ord-b5785b74de6d46e1834f7a888df8b4db
Source dataset
uspto-grants-2012_11
Patent number
US08309580B2

Reaction notes

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