HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Fluoro-2-methylphenyl)boronic acid → Methyl 5-(4-fluoro-2-methylphenyl)-2-methyl-3-furoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Fluoro-2-methylphenyl)boronic acid | HCID 2734665 | — |
| Reactant | Methyl 5-bromo-2-methylfuran-3-carboxylate | HCID 15534190 | — |
| Product | Methyl 5-(4-fluoro-2-methylphenyl)-2-methyl-3-furoate | HCID 68515415 | 85% |
Reaction Steps
An operation similar to that in Example 49 (2) was performed using methyl 5-bromo-2-methyl-3-furoate (4.4 g) and 4-fluoro-2-methylphenylboronic acid (3.7 g) to give the title compound (4.2 g, 85%) as a white crystal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309580B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-e0684a6fff9347809873f7e39b59413b |
| Source note | uspto-grants-2012_11 |