Thionyl Chloride → HCID 68514310, compound

HRID 1877033Notes

Reaction equation

HRID 1877033 reaction equation
[CH:1]1([CH:5]([C:7]2[CH:11]=[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[O:9][C:8]=2[CH3:18])O)[CH2:4][CH2:3][CH2:2]1.S(Cl)([Cl:21])=O>C1(C)C=CC=CC=1>[Cl:21][CH:5]([CH:1]1[CH2:4][CH2:3][CH2:2]1)[C:7]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[O:9][C:8]=1[CH3:18]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 68515959HCID 68515959, compound

Product 1

HCID 68514310HCID 68514310, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To a solution of cyclobutyl(2-methyl-5-phenylfuran-3-yl)methanol (1.3 g) in toluene (10 mL) was added thionyl chloride (1.2 mL), and the mixture was stirred at room temperature overnight. The solvent was evaporated under reduced pressure to give the title compound (1.4 g, 100%) as an oil.

Workup

  1. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-4d9d3c4766724052ac42e402c71bb80a
Source dataset
uspto-grants-2012_11
Patent number
US08309580B2

Reaction notes

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