Water → HCID 68514512, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of cyclohexyl{3-methyl-5-[4-(trifluoromethyl)phenyl]furan-2-yl}methanol (0.7 g) in dichloromethane (5 mL) were added oxalyl chloride (0.3 mL) and triethylamine (0.5 mL) at 0° C., and the mixture was stirred at 0° C. for 1 hr. The reaction mixture was poured into water, and the mixture was extracted with ethyl acetate. The organic layer was washed with saturated brine, and dried over magnesium sulfate. The solvent was evaporated under reduced pressure to give the title compound (0.8 g, 100%).

Provenance & Evidence