HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-[Chloro(cyclopentyl)methyl]-2-methyl-5-phenylfuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Cyclopentyl(2-methyl-5-phenylfuran-3-yl)methanol | HCID 68509772 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-[Chloro(cyclopentyl)methyl]-2-methyl-5-phenylfuran | HCID 68514089 | 100% |
Reaction Steps
To a solution of cyclopentyl(2-methyl-5-phenylfuran-3-yl)methanol (0.9 g) in toluene (20 mL) was added thionyl chloride (0.5 mL), and the mixture was stirred at room temperature overnight. The solvent was evaporated under reduced pressure to give the title compound (1.0 g, 100%) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309580B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-33ed6ed5150244c3820f26b7b43f1c9b |
| Source note | uspto-grants-2012_11 |