Hydrogen chloride-ethyl acetate → HCID 86646377, compound

HRID 1877080Notes

Reaction equation

HRID 1877080 reaction equation
C(O[C:6]([N:8](C)[CH2:9][CH:10]([OH:15])[C:11]([O:13][CH3:14])=[O:12])=O)(C)(C)C.[ClH:17].C(OCC)(=O)C>>[ClH:17].[OH:15][CH:10]([CH2:9][NH:8][CH3:6])[C:11]([O:13][CH3:14])=[O:12]

Participants

3

Reactant 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 86646376HCID 86646376, compound

Product 1

HCID 86646377HCID 86646377, compoundYield 100%

Procedure

A mixture of methyl 3-[(tert-butoxycarbonyl)(methyl)amino]-2-hydroxypropanoate (0.2 g) and 4N hydrochloric acid-ethyl acetate (5 mL) was stirred at room temperature for 1 hr. The solvent was evaporated under reduced pressure, to give the title compound (0.1 g, 100%) as a yellow crystal.

Workup

  1. customThe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-503abdaf3a4e4a959071d5ba2faa4438
Source dataset
uspto-grants-2012_11
Patent number
US08309580B2

Reaction notes

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