Diethyl Ether → HCID 68439530, compound

HRID 1877333Notes

Reaction equation

HRID 1877333 reaction equation
[C:1]1([C@H:7]([CH2:11]C(O)=O)[C:8]([OH:10])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:15][Li].C([O:19][CH2:20][CH3:21])C>>[C:1]1([C@H:7]([CH2:11][C:20](=[O:19])[CH3:21])[C:8](=[O:10])[CH3:15])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 736146(2S)-2-Phenylbutanedioic acidHCID 178418348HCID 178418348, compound

Product 1

HCID 68439530HCID 68439530, compound

Procedure

(S)-3-Phenylhexane-2,5-dione was synthesized from (S)-2-phenylsuccinic acid with methyllithium in diethyl ether. The analytical data apart from the optical rotation and CD corresponds to the product formed by means of PigD catalysis (FIGS. 10 and 16).

Workup

  1. customThe analytical data apart from the optical rotation and CD corresponds to the product formed by means of PigD catalysis (FIGS. 10 and 16)

Sources & evidence

ORD record
ord-df9c327b807241d2a597305e2eeddc6b
Source dataset
uspto-grants-2012_11
Patent number
US08309742B2

Reaction notes

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