HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methyl-1,2,3,4-tetrahydroquinoline → [2-(3-Chloro-phenoxy)-pyridin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methyl-1,2,3,4-tetrahydroquinoline | HCID 66678 | — |
| Reactant | 1,2,3,4-Tetrahydroquinoline | HCID 69460 | — |
| Reactant | 2-(3-Chlorophenoxy)nicotinic acid | HCID 12202641 | — |
| Product | [2-(3-Chloro-phenoxy)-pyridin-3-yl]-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)-methanone | HCID 59294538 | — |
Reaction Steps
The title compound was prepared in analogy to Example 1, Step 2, replacing 2-(3-trifluoromethyl-phenoxy)-nicotinic acid with 2-(3-chloro-phenoxy)-nicotinic acid (Example 3, Step 1) and 1,2,3,4-tetrahydro-quinoline with 6-methyl-1,2,3,4-tetrahydro-quinoline ([CAS RN 91-61-2]). MS (ISP): 379.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309734B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-74ba4384a84e4df09a8d8809201723e0 |
| Source note | uspto-grants-2012_11 |