HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Ethylaniline → 2-(2,5-Dichloro-phenoxy)-N-ethyl-5-fluoro-N-phenyl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Ethylaniline | HCID 7670 | — |
| Reactant | 6-Methyl-1,2,3,4-tetrahydroquinoline | HCID 66678 | — |
| Reactant | 2-(2,5-Dichloro-phenoxy)-5-fluoro-nicotinic acid | HCID 67367443 | — |
| Product | 2-(2,5-Dichloro-phenoxy)-N-ethyl-5-fluoro-N-phenyl-nicotinamide | HCID 59294480 | — |
Reaction Steps
The title compound was prepared in analogy to Example 31, Step 2, replacing 2-(2,5-dichloro-phenoxy)-nicotinic acid with 2-(2,5-dichloro-phenoxy)-5-fluoro-nicotinic acid (Example 80, Step 1) and 6-methyl-1,2,3,4-tetrahydro-quinoline with ethyl-phenyl-amine ([CAS RN 103-69-5]). MS (ISP): 405.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309734B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-55f6d77ffa6e4e19a89e02bc49000943 |
| Source note | uspto-grants-2012_11 |