HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,3,4-Tetrahydroquinoline → (3-Bromo-pyridin-4-yl)-(2,3-dihydro-benzo[1,4]oxazin-4-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,3,4-Tetrahydroquinoline | HCID 69460 | — |
| Reactant | 3,4-Dihydro-2H-1,4-benzoxazine | HCID 585096 | — |
| Reactant | 3-Bromoisonicotinic acid | HCID 817972 | — |
| Product | (3-Bromo-pyridin-4-yl)-(2,3-dihydro-benzo[1,4]oxazin-4-yl)-methanone | HCID 67378149 | — |
Reaction Steps
The title compound was prepared in analogy to Example 6, Step 1, replacing 2-chloro-nicotinic acid with 3-bromo-isonicotinic acid [CAS RN 13959-02-9]) and 1,2,3,4-tetrahydro-quinoline with 3,4-dihydro-2H-benzo[1,4]oxazine ([CAS RN 5735-53-5]). MS (ISP): 319.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08309734B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-8111fdec729446678c7938499c0d8b98 |
| Source note | uspto-grants-2012_11 |