huagongshe.com
HRID1878106

反应详情

EQUATION

反应方程式

HRID 1878106 的结构方程式

REACTANTS

反应物

2
结构：Cc1cccc(N2CCNCC2)c1
HCID83111

1-(m-Tolyl)piperazine

C11H16N2

结构：CCOC(=O)Nc1nc2cc(F)ccc2nc1OC
HCID66917965

未命名化合物

PRODUCTS

生成物

1
结构：COc1nc2ccc(F)cc2nc1NC(=O)N1CCN(c2cccc(C)c2)CC1
HCID11675599

N-(7-Fluoro-3-methoxy-2-quinoxalinyl)-4-(3-methylphenyl)-1-piperazinecarboxamide

C21H22FN5O2

收率 90%

PROCEDURE

实验过程

Ethyl N-(6-fluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(3-methylphenyl)piperazine were reacted by the same way with the example 1 to obtain the titled compound (yield, 90%). 1H NMR (200 MHz, CDCl3): δ 2.33 (s, 3H), 3.26-3.30 (m, 4H), 3.74-3.78 (m, 3H), 4.13 (s, 4H), 6.75-6.78 (m, 3H), 7.14-7.28 (m, 2H), 7.36 (s, 1H), 7.44-7.51 (dd, J=9.8 and 2.4 Hz, 1H), 7.67-7.74 (m, 1H).