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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1878202Generated: November 1, 2026

Piperazin-4-ylacetophenone → HCID 69242445, compound

https://huagongshe.com/reaction/1878202

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazin-4-ylacetophenoneHCID 97269—
Reactantethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamateHCID 69243333—
ProductHCID 69242445HCID 6924244591%

Reaction Steps

Ethyl N-(6-fluoro-3-methoxyquinoxalin-2-yl)carbamate and 1-(4-acetylphenyl)piperazine were reacted by the same way with the example 85 to obtain the titled compound (yield, 91%). 1H NMR (200 MHz, CDCl3): δ 2.54 (s, 3H), 3.50 (s, 4H), 3.90 (s, 4H), 4.15 (s, 3H), 6.89 (d, J=8.7 Hz, 2H), 7.25-7.62 (m, 3H), 7.79 (s, 1H), 7.91 (d, J=9.0 Hz, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314100B2
Source datasetuspto-grants-2012_11
ORD IDord-e1d7c97e7825450caf3b97779117e1f9
Source noteuspto-grants-2012_11