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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1878236Generated: October 26, 2026

1-(3,5-Dimethoxyphenyl)piperazine → 1-[(3-Methoxy-6-methylquinoxalin-2-yl)aminocarbonyl]-4-(3,5-dimethoxyphenyl)piperazine

https://huagongshe.com/reaction/1878236

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3,5-Dimethoxyphenyl)piperazineHCID 2736205—
Reactantethyl N-(3-methoxy-6-methylquinoxalin-2-yl)carbamateHCID 69243736—
Product1-[(3-Methoxy-6-methylquinoxalin-2-yl)aminocarbonyl]-4-(3,5-dimethoxyphenyl)piperazineHCID 6924440088%

Reaction Steps

Ethyl N-(3-methoxy-6-methylquinoxalin-2-yl)carbamate and 1-(3,5-dimethoxyphenyl)piperazine were reacted by the same way with the example 127 to obtain the titled compound (yield, 88%). MS (ESI) m/z 438 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314100B2
Source datasetuspto-grants-2012_11
ORD IDord-4c5a1d5ba25240059ffd1548c91d1241
Source noteuspto-grants-2012_11