Ethanol → 1-[1-{3-[4-(1H-Benzoimidazol-2-yl)-piperidin-1-yl]-2-hydroxy-propyl}-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone

HRID 187824Notes

Reaction equation

HRID 187824 reaction equation
[CH3:42][CH2:43][OH:44].[NH:1]1[CH2:2][CH2:3][CH:4]([c:7]2[n:8][c:9]3[c:10]([nH:11]2)[cH:12][cH:13][cH:14][cH:15]3)[CH2:5][CH2:6]1.[O:16]1[CH:17]([CH2:19][n:20]2[n:21][c:22](-[c:32]3[cH:33][cH:34][c:35]([C:38]([F:39])([F:40])[F:41])[cH:36][cH:37]3)[c:23]3[c:28]2[CH2:27][CH2:26][N:25]([C:29]([CH3:30])=[O:31])[CH2:24]3)[CH2:18]1>>[N:1]1([CH2:18][CH:17]([OH:16])[CH2:19][n:20]2[n:21][c:22](-[c:32]3[cH:33][cH:34][c:35]([C:38]([F:39])([F:40])[F:41])[cH:36][cH:37]3)[c:23]3[c:28]2[CH2:27][CH2:26][N:25]([C:29]([CH3:30])=[O:31])[CH2:24]3)[CH2:2][CH2:3][CH:4]([c:7]2[n:8][c:9]3[c:10]([nH:11]2)[cH:12][cH:13][cH:14][cH:15]3)[CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 702EthanolHCID 7158102-(piperidin-4-yl)-1H-1,3-benzodiazoleHCID 222938171-[1-Oxiranylmethyl-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone

Product 1

HCID 101205671-[1-{3-[4-(1H-Benzoimidazol-2-yl)-piperidin-1-yl]-2-hydroxy-propyl}-3-(4-trifluoromethyl-phenyl)-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-5-yl]-ethanone

Sources & evidence

ORD record
ord-a83ed116362946ec92d2de7fb97f5849
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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