1-(4-Fluorophenyl)piperazine → 1-[(3,6-Dimethoxyquinoxalin-2-yl)aminocarbonyl]-4-(4-fluorophenyl)piperazine

Participants

Reaction Steps

Ethyl N-(3,6-dimethoxyquinoxalin-2-yl)carbamate and 1-(4-fluorophenyl)piperazine were reacted by the same way with the example 148 to obtain the titled compound (yield, 92%). 1H NMR (300 MHz, CDCl3): δ 3.17 (s, 4H), 3.75 (s, 4H), 3.89 (s, 3H), 4.12 (s, 3H), 6.86-7.01 (m, 4H), 7.13 (s, 2H), 7.32 (s, 1H), 7.72-7.74 (m, 1H).

Provenance & Evidence