1-(m-Tolyl)piperazine → 1-[(6,7-Difluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3-methylphenyl)piperazine

Participants

Reaction Steps

Ethyl N-(6,7-di fluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(3-methyl phenyl)piperazine were reacted by the same way with the example 169 to obtain the titled compound (yield, 66%). 1H NMR (300 MHz, CDCl3) δ 2.34 (s, 3H), 3.27-3.29 (m, 4H), 3.75-3.77 (m, 4H), 4.15 (s, 3H), 6.75-6.78 (m, 4H), 7.18-7.21 (m, 1H), 7.49-7.53 (m, 1H), 7.58-7.62 (m, 1H).

Provenance & Evidence