1-(3,5-Dimethylphenyl)piperazine → 1-[(6,7-Difluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethylphenyl)piperazine

Participants

Reaction Steps

Ethyl N-(6,7-di fluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(3,5-dimethyl phenyl)piperazine were reacted by the same way with the example 169 to obtain the titled compound (yield, 70%). 1H NMR (300 MHz, CDCl3) δ 2.30 (s, 6H), 3.26-3.28 (m, 4H), 3.74-3.76 (m, 4H), 4.15 (s, 3H), 6.59 (s, 3H), 7.29 (s, 1H), 7.49-7.53 (m, 1H), 7.52-7.62 (m, 1H).

Provenance & Evidence