1-(3-Bromophenyl)piperazine → 1-[(6,7-Difluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl]-4-(3-bromophenyl)piperazine

Participants

Reaction Steps

Ethyl N-(6,7-di fluoro-2-methoxyquinoxalin-3-yl)carbamate and 1-(3-bromo phenyl)piperazine were reacted by the same way with the example 169 to obtain the titled compound (yield, 58%). 1H NMR (300 MHz, CDCl3) δ 3.30 (m, 4H), 3.76 (m, 4H), 4.15 (s, 3H), 6.85-6.87 (m, 1H), 7.02-7.03 (m, 2H), 7.06-7.07 (m, 1H), 7.13-7.16 (m, 1H), 7.30 (br s, 1H), 7.51-7.53 (m, 1H), 7.60 (br s, 1H).

Provenance & Evidence