Ethyl 6-[1-(triisopropylsilyl)-1H-pyrrol-3-yl]imidazo[1,2-a]pyridine-2-carboxylate → HCID 178469438, compound

HRID 1878484Notes

Reaction equation

HRID 1878484 reaction equation
C([Si](C(C)C)(C(C)C)[N:5]1[CH:9]=[CH:8][C:7]([C:10]2[CH:11]=[CH:12][C:13]3[N:14]([CH:16]=[C:17]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[N:18]=3)[CH:15]=2)=C1)(C)C.[NH:30]1C=CC(B(O)O)=N1>>[NH:5]1[CH:9]=[CH:8][C:7]([C:10]2[CH:11]=[CH:12][C:13]3[N:14]([CH:16]=[C:17]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[N:18]=3)[CH:15]=2)=[N:30]1

Participants

3

Reactant 2

HCID 44136203Ethyl 6-[1-(triisopropylsilyl)-1H-pyrrol-3-yl]imidazo[1,2-a]pyridine-2-carboxylateHCID 178514837HCID 178514837, compound

Product 1

HCID 178469438HCID 178469438, compound

Procedure

This product is prepared under conditions similar to those described for the preparation of Intermediate 15 (step 15.1), replacing the 1-(triisopropylsilyl)pyrrole-3-boronic acid with pyrazole-3-boronic acid.

Workup

  1. customThis product is prepared under conditions similar to

Sources & evidence

ORD record
ord-4b9fe28ddd524b22be251878b0f7c233
Source dataset
uspto-grants-2012_11
Patent number
US08314109B2

Reaction notes

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