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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1878489Generated: October 31, 2026

6-(6-{[(1,1-Dimethylethoxy)carbonyl]amino}pyridin-2-yl)imidazo[1,2-a]pyridine-2-carboxylic acid → 6-(Furan-2-yl)imidazo[1,2-a]pyridine-2-carboxylic acid

https://huagongshe.com/reaction/1878489

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(6-{[(1,1-Dimethylethoxy)carbonyl]amino}pyridin-2-yl)imidazo[1,2-a]pyridine-2-carboxylic acidHCID 44124940—
ReactantEthyl 6-(furan-2-yl)imidazo[1,2-a]pyridine-2-carboxylateHCID 44136206—
Product6-(Furan-2-yl)imidazo[1,2-a]pyridine-2-carboxylic acidHCID 4412507574.9%

Reaction Steps

384 mg of ethyl 6-(furan-2-yl)imidazo[1,2-a]pyridine-2-carboxylate are saponified under conditions similar to those described for the preparation of Intermediate 11 (step 11.3) to give 256 mg of 6-(furan-2-yl)imidazo[1,2-a]pyridine-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314109B2
Source datasetuspto-grants-2012_11
ORD IDord-bcf881c472da4fdeb8d09d58aa59c562
Source noteuspto-grants-2012_11