Morpholine → HCID 58531010, compound

Participants

Reaction Steps

There was dissolved, in 1,4-dioxane (5 mL), 5,7-dichloro-2-(4-chlorophenyl)-pyrazolo[1,5-a]pyrimidine (200 mg, 0.670 mM), then morpholine (117 μL, 1.34 mM) was added to the solution and the mixture was stirred at room temperature for 30 minutes. The solvent was distilled off from the reaction mixture and the resulting residue was diluted with water and extracted with methylene chloride. The extracts thus obtained were combined, dried over anhydrous sodium sulfate, the solvent was distilled off and then the resulting solid was washed with methanol to give the title compound (222 mg, yield: 94%).

Provenance & Evidence