Morpholine → HCID 58531038, compound

Participants

Reaction Steps

There was dissolved, in 1,4-dioxane (4 mL), 5,7-dichloro-2-thiophen-2-yl-pyrazolo[1,5-a]pyrimidine (184 mg, 0.679 mM), then morpholine (118 μL, 1.36 mM) was added to the solution and the mixture was stirred at room temperature for 2 hours. The solvent was distilled off from the reaction mixture, the residue was diluted with water and then extracted with methylene chloride. The extracts thus obtained were combined, dried over anhydrous sodium sulfate, the solvent was then distilled off and the resulting solid was washed with methanol to thus give the title compound (114 mg, yield: 52%).

Provenance & Evidence