Acetic Acid → HCID 70999680, compound

Participants

Reaction Steps

To a solution of 7-morpholin-4-yl-2-phenyl-pyrazolo[1,5-a]pyrimidin-5-yl-hydrazine (20 mg, 0.065 mM) in absolute ethanol (2.0 mL), there were added 2,2-dimethyl-2,3-dihydro-benzofuran (17 mg, 0.097 mM) and acetic acid (2.0 μL) and the mixture was stirred at room temperature for 3 hours. Water was added to the mixture, the mixture was then extracted with ethyl acetate and then the resulting organic phase was washed with a saturated aqueous common salt solution. After the drying of the organic phase over anhydrous magnesium sulfate, the organic phase was concentrated under reduced pressure. The resulting residue was purified by the NH-silica gel column chromatography (ethyl acetate:hexane=1:2) to thus give the title compound (18 mg, yield: 60%).

Provenance & Evidence