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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1878574Generated: November 1, 2026

Acetic Acid → HCID 136351087, compound

https://huagongshe.com/reaction/1878574

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantIndole-3-CarboxaldehydeHCID 10256—
ReactantHCID 70999551HCID 70999551—
SolventEthanolHCID 702—
ProductHCID 136351087HCID 13635108751.1%

Reaction Steps

To a solution of (7-morpholin-4-yl-3-pyridin-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine (25 mg, 0.080 mM) in ethanol (1.5 mL), there were added 3-formyl-indole (18 mg, 0.12 mM) and acetic acid (3 μL) and then the mixture was stirred at room temperature for 3 hours. The precipitated solid was recovered through filtration and then washed with ethanol to thus give the title compound (18 mg, yield: 51%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314098B2
Source datasetuspto-grants-2012_11
ORD IDord-38507e28a5c74dcabe1a36a73d6ccd4f
Source noteuspto-grants-2012_11