HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 136351087, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Indole-3-Carboxaldehyde | HCID 10256 | — |
| Reactant | HCID 70999551 | HCID 70999551 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 136351087 | HCID 136351087 | 51.1% |
Reaction Steps
To a solution of (7-morpholin-4-yl-3-pyridin-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine (25 mg, 0.080 mM) in ethanol (1.5 mL), there were added 3-formyl-indole (18 mg, 0.12 mM) and acetic acid (3 μL) and then the mixture was stirred at room temperature for 3 hours. The precipitated solid was recovered through filtration and then washed with ethanol to thus give the title compound (18 mg, yield: 51%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314098B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-38507e28a5c74dcabe1a36a73d6ccd4f |
| Source note | uspto-grants-2012_11 |