HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 136351088, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Indole-3-Carboxaldehyde | HCID 10256 | — |
| Reactant | HCID 70999539 | HCID 70999539 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 136351088 | HCID 136351088 | 54% |
Reaction Steps
To a solution of (7-Morpholin-4-yl-2-pyrazin-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine (20 mg, 0.064 mM) in ethanol (2.0 mL), there were added 3-formyl-indole (19 mg, 0.13 mM) and acetic acid (5 μL) and the mixture was stirred at room temperature for 3 hours. The precipitated solid was recovered through filtration and then washed with ethanol to thus give the title compound (15 mg, yield: 54%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314098B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-408922e1208f477994c4c96b3d248ba6 |
| Source note | uspto-grants-2012_11 |