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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1878575Generated: November 4, 2026

Acetic Acid → HCID 136351088, compound

https://huagongshe.com/reaction/1878575

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantIndole-3-CarboxaldehydeHCID 10256—
ReactantHCID 70999539HCID 70999539—
SolventEthanolHCID 702—
ProductHCID 136351088HCID 13635108854%

Reaction Steps

To a solution of (7-Morpholin-4-yl-2-pyrazin-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine (20 mg, 0.064 mM) in ethanol (2.0 mL), there were added 3-formyl-indole (19 mg, 0.13 mM) and acetic acid (5 μL) and the mixture was stirred at room temperature for 3 hours. The precipitated solid was recovered through filtration and then washed with ethanol to thus give the title compound (15 mg, yield: 54%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314098B2
Source datasetuspto-grants-2012_11
ORD IDord-408922e1208f477994c4c96b3d248ba6
Source noteuspto-grants-2012_11