HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 137252529, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Indole-3-Carboxaldehyde | HCID 10256 | — |
| Reactant | HCID 70999566 | HCID 70999566 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 137252529 | HCID 137252529 | 47.3% |
Reaction Steps
There was suspended, in ethanol (3.0 mL), [2-(6-methyl-pyridin-3-yl)-7-morpholin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl]-hydrazine (70 mg, 0.22 mM), then acetic acid (6.3 μL, 0.11 mM) and indole-3-carboxy-aldehyde (35 mg, 0.24 mM) were added to the suspension and the mixture was stirred at room temperature for 16 hours. The precipitated solid was recovered through filtration and then washed with diethyl ether to thus give the title compound (46 mg, yield: 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314098B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-5bdfa5a581584309addb76d6aca7e32a |
| Source note | uspto-grants-2012_11 |