Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1878579Generated: November 2, 2026

Acetic Acid → HCID 137252529, compound

https://huagongshe.com/reaction/1878579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantIndole-3-CarboxaldehydeHCID 10256—
ReactantHCID 70999566HCID 70999566—
SolventEthanolHCID 702—
ProductHCID 137252529HCID 13725252947.3%

Reaction Steps

There was suspended, in ethanol (3.0 mL), [2-(6-methyl-pyridin-3-yl)-7-morpholin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl]-hydrazine (70 mg, 0.22 mM), then acetic acid (6.3 μL, 0.11 mM) and indole-3-carboxy-aldehyde (35 mg, 0.24 mM) were added to the suspension and the mixture was stirred at room temperature for 16 hours. The precipitated solid was recovered through filtration and then washed with diethyl ether to thus give the title compound (46 mg, yield: 47%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08314098B2
Source datasetuspto-grants-2012_11
ORD IDord-5bdfa5a581584309addb76d6aca7e32a
Source noteuspto-grants-2012_11