HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-Bromo-pyridin-3-yl)-2-(6-methyl-pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidine → 4-(5-Bromo-pyridin-3-yl)-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-Bromo-pyridin-3-yl)-2-(6-methyl-pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidine | HCID 44194448 | — |
| Reactant | 4-iodo-2-(6-methyl-pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidine | HCID 86632429 | — |
| Reactant | 4-iodo-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine | HCID 86632430 | — |
| Product | 4-(5-Bromo-pyridin-3-yl)-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine | HCID 68760142 | — |
Reaction Steps
4-(5-Bromo-pyridin-3-yl)-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine is prepared by an analogous method to that for 4-(5-bromo-pyridin-3-yl)-2-(6-methyl-pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidine (Example 16) by replacing 4-iodo-2-(6-methyl-pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidine (Intermediate 3) with 4-iodo-2-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine (Intermediate 4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314112B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-5144dae81c5e4dacb80d0efba6205430 |
| Source note | uspto-grants-2012_11 |