HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 2-chloro-N-phenyloxazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Ethyl 2-chlorooxazole-4-carboxylate | HCID 2763184 | — |
| Product | 2-chloro-N-phenyloxazole-4-carboxamide | HCID 68804496 | — |
Reaction Steps
Prepared from ethyl 2-chlorooxazole-4-carboxylate (45.4 mg, 0.258 mmol) and aniline (24 mg, 0.258 mmol) as described in Example 154A: 1H NMR (500 MHz, methanol-D4) δ ppm 7.13-7.18 (m, 1H), 7.32-7.38 (m, 2H), 7.65-7.71 (m, 2H), 8.53 (s, 1H). MS (APCI) m/z=223 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08314119B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-a4edbbabd1584b7ea025f0c607410cac |
| Source note | uspto-grants-2012_11 |