HCID 24988252, compound → HCID 131730069, compound

HRID 1878683Notes

Reaction equation

HRID 1878683 reaction equation
[ClH:1].[C:2]1([C:8]2[S:12][C:11]([O:13][C@@H:14]3[CH:21]4[CH2:22][N:17]5[CH2:18][CH:19]([CH2:23][CH:15]3[CH2:16]5)[CH2:20]4)=[N:10][N:9]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>O>[OH2:13].[ClH:1].[C:2]1([C:8]2[S:12][C:11]([O:13][C@@H:14]3[CH:21]4[CH2:22][N:17]5[CH2:18][CH:19]([CH2:23][CH:15]3[CH2:16]5)[CH2:20]4)=[N:10][N:9]=2)[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1.[OH2:13].[OH2:13].[C:2]1([C:8]2[S:12][C:11]([O:13][C@@H:14]3[CH:21]4[CH2:22][N:17]5[CH2:18][CH:19]([CH2:23][CH:15]3[CH2:16]5)[CH2:20]4)=[N:10][N:9]=2)[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1.[ClH:1]

Participants

3

Reactant 1

HCID 24988252HCID 24988252, compound

Product 1

HCID 131730069HCID 131730069, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

(4s)-4-(5-Phenyl-1,3,4-thiadiazol-2-yloxy)-1-azatricyclo[3.3.1.13,7]decane hydrochloride quarterhydrate solid, 50 mg, was suspended of in 200 μL of water., (4s)-4-(5-Phenyl-1,3,4-thiadiazol-2-yloxy)-1-azatricyclo[3.3.1.13,7]decane hydrochloride sesquihydrate crystallized over time.

Workup

  1. custom, (4s)-4-(5-Phenyl-1,3,4-thiadiazol-2-yloxy)-1-azatricyclo[3.3.1.13,7]decane hydrochloride sesquihydrate crystallized over time

Sources & evidence

ORD record
ord-b8233cea1d2447989142be0f2e95c586
Source dataset
uspto-grants-2012_11
Patent number
US08314119B2

Reaction notes

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