Trifluoroacetic acid → HCID 59843100, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of tert-butyl 2-(2-oxo-5-(thiophen-2-yl)pyridin-1(2H)-yl)ethylcarbamate (125 mg, 390 μmol) in CH2Cl2 (1 mL) was added TFA (5 mL) and stirred for 30 min at 23° C. Solvents removed under reduced pressure and residue partioned between CH2Cl2 (10 mL) and 1M NaOH (5 mL). The organic layer was dried over MgSO4 and reduced to a brown oil under reduced pressure. MS (ESI pos. ion) m/z (MH+): 221 (MH+). Calc'd exact mass for C11H12N2OS: 220.

Provenance & Evidence