Potassium Carbonate → HCID 59843091, compound

Participants

Reaction Steps

Sodium triacetoxyborohydride (200 mg, 944 μmol) was added to a mixture of 4-(2-(3-(3-(aminomethyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethoxy)-7-methoxyquinoline-6-carbaldehyde (16 mg, 37 μmol) in CHCl3 (3 mL) and MeOH (1 mL) were added (to keep solvent volume). After 19 h, K2CO3 (500 mg) was added. After 3 h, the mixture was filtered and concentrated. The residue was purified on silica (5% (2 N NH3-MeOH) in CH2Cl2 to give a film (10 mg, 62%). LCMS (ESI pos. ion): calc'd for C24H24N4O4: 432.2; found 433.2 (M+1).

Provenance & Evidence